I randomly wanted to find out the highest placed artists that I've only scrobbled one song by:

58 scrobbles - Zac Efron (Rewrite the Stars)

47 - Lea Michele (Cannonball)

45 - A Great Big World (Say Something)

44 - Klingande (Jubel)

42 - Sexyy Red (Fat Juicy & Wet)

41 - The Pogues (Fairytale of New York)

39 - Little Nikki (Little Nikki Says)

33 - Disco Lines (No Broke Boys)

31 - Wizzard (I Wish It Could Be Christmas Everyday)

31 - Prince Royale (Back It Up)

I'm not sure which of those artists I'd be most intrigued to hear a second song by!

https://lastfmlists.com/

Great idea - I've had a look through my most scrobbled, and there are a lot of artists to whom I've given their next most played song 1 scrobble, but the highest with no other scrobbles at all is a song I've just written about in my 2025 EOY, followed by a clutch of my BJSC entries:

25 Ailith - Drought

24 KÄSSY - i-i-i

24 Mirella - Timanttei

24 Yakima Jera - Dertlı Dolap *

23 Hallan - The Colline Gate

*I definitely have listened to other songs of theirs, must have been on youtube

Bobby Helms - Jingle Bell Rock is the first commercial hit to appear, with 21.

Rolling year-end #1 songs:

08/2013: Avicii - I Could Be The One [124]

09/2013: Avicii - I Could Be The One [130]

10/2013: Avicii - I Could Be The One [130]

11/2013: Avicii - I Could Be The One [132]

12/2013: Avicii - Wake Me Up [141]

01/2014: Avicii - Wake Me Up [153]

02/2014: Avicii - Wake Me Up [165]

03/2014: Avicii - Wake Me Up [171]

04/2014: Avicii - Wake Me Up [174]

05/2014: Avicii - Wake Me Up [175]

06/2014: Avicii - Wake Me Up [163]

07/2014: Mr Probz - Waves (Robin Schulz Edit) [138]

08/2014: Mr Probz - Waves (Robin Schulz Edit) [149]

09/2014: Mr Probz - Waves (Robin Schulz Edit) [157]

10/2014: Mr Probz - Waves (Robin Schulz Edit) [164]

11/2014: Mr Probz - Waves (Robin Schulz Edit) [174]

12/2014: Mr Probz - Waves (Robin Schulz Edit) [185]

01/2015: Mr Probz - Waves (Robin Schulz Edit) [193]

02/2015: Mr Probz - Waves (Robin Schulz Edit) [175]

03/2015: Mr Probz - Waves (Robin Schulz Edit) [147]

04/2015: Mr Probz - Waves (Robin Schulz Edit) [119]

05/2015: Mr Probz - Waves (Robin Schulz Edit) [96]

06/2015: Kygo - Firestone [99]

07/2015: Kygo - Firestone [105]

08/2015: Omi - Cheerleader (Felix Jaehn Remix) [114]

09/2015: Omi - Cheerleader (Felix Jaehn Remix) [119]

10/2015: Avicii - Waiting For Love [120]

11/2015: Avicii - Waiting For Love [128]

12/2015: Avicii - Waiting For Love [136]

01/2016: Avicii - Waiting For Love [139]

02/2016: Avicii - Waiting For Love [142]

03/2016: Avicii - Waiting For Love [144]

04/2016: Avicii - Waiting For Love [145]

05/2016: Avicii - Waiting For Love [128]

06/2016: Sigala - Sweet Lovin' [95]

07/2016: Sigala - Sweet Lovin' [98]

08/2016: Sigala - Sweet Lovin' [99]

09/2016: Sigala - Sweet Lovin' [100]

10/2016: Era Istrefi - Bonbon [94]

11/2016: Era Istrefi - Bonbon [99]

12/2016: Martin Solveig - Do It Right [113]

01/2017: Martin Solveig - Do It Right [123]

02/2017: Martin Solveig - Do It Right [133]

03/2017: Martin Solveig - Do It Right [140]

04/2017: Martin Solveig - Do It Right [133]

05/2017: Martin Solveig - Do It Right [135]

06/2017: Mark Knight - Yebisah [124]

07/2017: Mark Knight - Yebisah [125]

08/2017: Jax Jones - You Don't Know Me [127]

09/2017: Jax Jones - You Don't Know Me [138]

10/2017: Jax Jones - You Don't Know Me [150]

11/2017: Jax Jones - You Don't Know Me [159]

12/2017: Jax Jones - You Don't Know Me [157]

01/2018: Jax Jones - You Don't Know Me [150]

02/2018: Jax Jones - You Don't Know Me [143]

03/2018: Avicii - Lonely Together [138]

04/2018: Avicii - Lonely Together [153]

05/2018: Avicii - Lonely Together [165]

06/2018: Avicii - Lonely Together [176]

07/2018: Avicii - Lonely Together [189]

08/2018: Avicii - Lonely Together [174]

09/2018: Avicii - Lonely Together [153]

10/2018: Avicii - Lonely Together [136]

11/2018: Avicii - Lonely Together [123]

12/2018: Avicii - Lonely Together [112]

01/2019: Calvin Harris - One Kiss [123]

02/2019: Calvin Harris - One Kiss [129]

03/2019: Calvin Harris - One Kiss [130]

04/2019: Super8 & Tab - Burn [127]

05/2019: Super8 & Tab - Burn [138]

06/2019: Super8 & Tab - Burn [138]

07/2019: Super8 & Tab - Burn [131]

08/2019: Super8 & Tab - Burn [126]

09/2019: Super8 & Tab - Burn [116]

10/2019: Super8 & Tab - Burn [103]

11/2019: Super8 & Tab - Burn [94]

12/2019: Avicii - Heaven [104]

01/2020: Avicii - Heaven [113]

02/2020: Avicii - Heaven [121]

03/2020: Avicii - Heaven [132]

04/2020: Avicii - Heaven [140]

05/2020: Avicii - Heaven [148]

06/2020: Avicii - Heaven [142]

07/2020: Avicii - Heaven [139]

08/2020: Avicii - Heaven [129]

09/2020: Avicii - Heaven [115]

10/2020: Avicii - Heaven [106]

11/2020: Boris Brejcha - Gravity [107]

12/2020: Boris Brejcha - Gravity [117]

01/2021: Boris Brejcha - Gravity [122]

02/2021: Boris Brejcha - Gravity [129]

03/2021: Boris Brejcha - Gravity [128]

04/2021: Boris Brejcha - Gravity [124]

05/2021: Adriatique - Home [117]

06/2021: Adriatique - Home [116]

07/2021: Adriatique - Home [110]

08/2021: Adriatique - Home [102]

09/2021: Grandbrothers - What We See [106]

10/2021: Grandbrothers - What We See [108]

11/2021: Grandbrothers - What We See [110]

12/2021: Grandbrothers - What We See [115]

01/2022: Grandbrothers - What We See [118]

02/2022: Shouse - Love Tonight [107]

03/2022: Embrz - Where You Are [116]

04/2022: Embrz - Where You Are [125]

05/2022: Embrz - Where You Are [135]

06/2022: Embrz - Where You Are [141]

07/2022: Embrz - Where You Are [133]

08/2022: Embrz - Where You Are [114]

09/2022: Bon Entendeur - Alba [103]

10/2022: Bon Entendeur - Alba [102]

11/2022: Redondo - All My Lovin [105]

12/2022: Redondo - All My Lovin [106]

01/2023: Redondo - All My Lovin [109]

02/2023: Redondo - All My Lovin [106]

03/2023: Grum - Look to the Light [96]

04/2023: Grum - Look to the Light [101]

05/2023: Grum - Look to the Light [108]

06/2023: Grum - Look to the Light [110]

07/2023: Grum - Look to the Light [104]

08/2023: Grum - Look to the Light [100]

09/2023: Grum - Look to the Light [95]

10/2023: Selker - Too Much For Me [94]

11/2023: Ram - What Matters [89]

12/2023: Ram - What Matters [96]

01/2024: Ram - What Matters [104]

02/2024: Calvin Harris - Miracle [103]

03/2024: Grandbrothers - North/South [92]

04/2024: Grandbrothers - North/South [83]

05/2024: Aname - Anywhere (Road Trippin) [78]

06/2024: Matt Guy - Every Little Time [77]

07/2024: Maribou State - Blackoak [80]

08/2024: Maribou State - Blackoak [86]

09/2024: Maribou State - Blackoak [92]

10/2024: Maribou State - Blackoak [94]

11/2024: Ben Hemsley - Closer [94]

12/2024: Ben Hemsley - Closer [103]

01/2025: Ben Hemsley - Closer [111]

02/2025: Ben Hemsley - Closer [120]

03/2025: Ben Hemsley - Closer [125]

04/2025: Ben Hemsley - Closer [111]

05/2025: Ben Hemsley - Closer [98]

06/2025: Klangphonics - Ghost (Find Me Again) [93]

07/2025: Klangphonics - Ghost (Find Me Again) [99]

08/2025: Klangphonics - Ghost (Find Me Again) [102]

09/2025: Klangphonics - Ghost (Find Me Again) [100]

10/2025: The Yagas - The Crying Room [90]

11/2025: The Yagas - The Crying Room [90]

12/2025: The Yagas - The Crying Room [88]

01/2026: Aname - Hopeful [89]